Spools were meant for strips, 1/4 mile and such. No damage going straight. Lots of spool options for popular strip diffs, like the venerable Ford 9".
Folks use them off road usually for one reason, they're cheaper than a lunch-box locker (the lockers Zooks use). A spool in a D60 under a CJ for a trailer queen is fine, and eliminates the typical problems associated with a locker (pin munch, sidegear wear, etc). In an anemic Zook axle, it's suicide.
In a Zook, personally, I think it's being pennywise and poundfoolish, especially if it will see asphalt or a lot of slickrock. Axles just can't take the sonstant stree over time, and the the money saved on the spool is spent on replacing shafts.
And being locked all the time is not always a good idea, especially for crawling, trail riding, or the road. Sometimes a locker, especially the front, can be the reason you have a problem on certain obsticles. Been there, done that, got the dent.
If you can spend the cash, or save until you can, a selectable locker is really the best way to go. Spooled when you need it, open when you don't. Axle stress reduced and shaft life extended tremendously. In the long run, you may spend more replacing shafts/fBirfs in spooled axles than the cost of the selectable locker.
That's my 2 cents.